News Release
Immunic highlights IMU-856 gastrointestinal candidate to mark International Celiac Day
Immunic Inc
Immunic Inc (NASDAQ:IMUX) chief scientific officer Hella Kohlhof joined Proactive's Stephen Gunnion on International Celiac Day, in the middle of Celiac Disease Awareness Month, to discuss the disease and the company’s developments in treating it. Kohlhof explained that celiac disease is a severe autoimmune disorder affecting around 1% of the global population, predominantly females. Unlike gluten intolerance, celiac disease involves an immune reaction to gluten, leading to gut inflammation and destruction. The only current treatment is a gluten-free diet, which is not effective for all patients. Kohlhof elaborated on the disease's scientific background, highlighting its genetic association with specific HLA genotypes (HLA-DQ2 and HLA-DQ8). She explained that celiac disease is triggered by the immune system's reaction to deaminated gluten peptides, causing inflammation and damage to the gut lining. Immunic is developing IMU-856, an epigenetic modulator, to treat gastrointestinal diseases like celiac disease. IMU-856 enhances gut regeneration and strengthens the gut barrier, improving patients' conditions. Kohlhof detailed the successful completion of a Phase 1b study in celiac patients, which demonstrated the drug’s safety, good pharmacokinetic properties, and positive effects on symptoms, biomarkers, gut histology, and nutrient uptake during a gluten challenge. The study confirmed the potential of IMU-856 in treating celiac disease, and further exploration of its mode of action is ongoing. Contact Details Proactive North America +1 604-688-8158 NA-editorial@proactiveinvestors.com
May 16, 2024 05:54 PM Eastern Daylight Time
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Lunnon Metals reports promising update on Foster South nickel project, progresses gold exploration
Lunnon Metals Ltd
Lunnon Metals Ltd (ASX:LM8, OTC:LNMLF) managing director and CEO Edmund Ainscough takes Proactive's Stephen Gunnion through a mineral resource update for the company's Foster South project, which he described as very encouraging. The project now boasts an updated mineral resource estimate of 375,000 tonnes with a 4.7% nickel content, which was based on recent metallurgical drilling. Ainscough highlighted significant historical data and the high recovery rates of the testing done, which contributed to an overall 10% increase in both tonnes and metal content without changing the grade. Foster South, a historical mine with a deep nine-kilometre decline, is positioned as a key target for development and mining upon any potential restart of the project. Despite the current negative sentiment towards nickel, Ainscough said the project's proximity to existing infrastructure and high-grade resources positions it well for future developments. He further noted the ongoing integration and evaluation with the Baker deposit, and the importance of external factors such as decisions from BHP on their nickel business which could affect third-party processing alternatives. Lastly, Ainscough touched upon the company's strategic pivot to gold exploration during the hiatus in its nickel program, leveraging the region's prolific gold belt. This dual-focused strategy aims to optimize resource development while awaiting further clarity on nickel market conditions. Contact Details Proactive Australia Pty Ltd +61 431 597 771 writers.australia@proactiveinvestors.com
May 16, 2024 05:40 PM Eastern Daylight Time
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Sabre Resources advances key uranium and lithium projects
SABRE RESOURCES LIMITED
Sabre Resources Ltd CEO Jon Dugdale joins Jonathan Jackson in the Proactive studio to discuss the company’s continued progress in its exploration and advancement of key energy metals and gold projects. The company is progressing projects in various significant Australian locations. Today saw the company define key lithium-pegmatite drilling targets along strike of the world-class Andover discovery. Further drone-magnetics data and imagery defined an outstanding target zone for the discovery of lithium-bearing pegmatites, only 5 kilometres northeast along strike from Azure Minerals’ Andover discovery (where intersections include 209.4m @ 1.42% Li2O1). The priority targets are located within Sabre's extensive approximate 300 sq.km tenement holdings in WA's highly prospective northwest Pilbara region. Sabre is in a strong financial position, with $5.3 million in cash at the quarter's end to support ongoing exploration efforts. Key recent developments include following up on high-grade uranium results at Dingo Uranium Project, where previous drilling identified substantial uranium concentrations. In the Northwest Pilbara, drone magnetics surveys over the Andover East and Northeast targets identified potential lithium-bearing pegmatite-hosting fault corridors. Similarly, in the Eastern Goldfields, new lithium anomalies were detected over a 5 x 5-kilometre area, indicating significant exploration potential in regions associated with notable lithium deposits. Additionally, Sabre's Ninghan Gold Project in the southern Murchison district also showed promising results with two strongly anomalous zones of gold mineralisation identified. Overall, Sabre’s extensive and strategically targeted exploration activities across multiple projects demonstrate its robust operational and financial footing, positioning it to effectively pursue these promising mineral opportunities. Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 jonathan@proactiveinvestors.com
May 16, 2024 03:30 PM Eastern Daylight Time
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Resouro Strategic Metals plans ASX listing, aims to raise A$8 million
RESOURO STRATEGIC METALS INC.
Resouro Strategic Metals Inc. (TSX-V: RSM) CEO Chris Eager sits down with Jonathan Jackson in the Proactive studio to discuss its planned listing on the Australian Securities Exchange (ASX). The Canadian-based mineral exploration and development company lodged a prospectus with the Australian Securities and Investments Commission (ASIC) on May 1, 2024, aiming to raise A$8 million at a price of A$0.50 each. This offering is scheduled to close on May 23, 2024, with trading on the ASX expected to start around June 4, 2024, pending satisfaction of ASX’s listing requirements. Upon successful ASX listing, Resouro's securities will be tradeable on four platforms: the TSX Venture Exchange, the Frankfurt Stock Exchange, the Over-the-Counter market in the USA, and the Australian Stock Exchange, enhancing investor accessibility. Resouro focuses on developing economic mineral projects in Brazil, including the rare earth and titanium Tiros Project in northern Minas Gerais, which covers about 450 square kilometres and holds several exploration permits. The company, through its Brazilian subsidiary, holds a 90% interest in this project, with the remaining 10% held by RBM Consultoria Mineral Eireli. Additionally, Resouro is involved in the Novo Mundo and Santa Angela gold projects, though the latter is not considered material to the company’s operations. Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 jonathan@proactiveinvestors.com
May 16, 2024 02:45 PM Eastern Daylight Time
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THE MTV OF INDEPENDENT FILM!
YourUpdateTV
The 6th Annual Transparent Film Festival is set to take place at the iconic Producers Club in midtown Manhattan's Theatre District on June 13th, this festival will not only feature some of the best in Indie Film from over 1000 submissions world-wide but will also include the launch of ABFAB.COM, it’s digital app free streaming platform. ABFAB.COM aims to be the go-to hub for indie filmmakers, akin to what MTV did for musicians when it debuted in 1981, but with an expanded scope. With a commitment to showcasing diverse talents from across the globe, ABFAB.COM is not only partnering with festivals like Transparent Film Festival but also welcoming submissions directly from content creators. Phase 2 of its launch will broaden its scope to include comedians, theater groups, musicians, and more, in line with the original MTV ethos of celebrating creativity in all its forms. Brian McLane, the founder of Transparent Film Festival, emphasizes the need for platforms like ABFAB.COM to provide exposure and recognition to independent filmmakers, echoing the success of the festival in highlighting the abundance of talent in the indie film scene. Through ABFAB.COM 's 24-hour streaming network, every content creator will have a chance to display their work without the clutter of an app. “We want to do everything we can to promote independent filmmaking and independent filmmakers, so having been around when MTV first came out and seeing what that did for the music world, we wanted to create ABFAB.COM so all types of films from all over the world will have a home and a place to get exposure”, said McLane. Embracing the spirit of MTV's on-air VJs, ABFAB.COM is gearing up for worldwide auditions to find presenters who embody unity and individualism, much like the iconic personalities of MTV's golden era. Festival Co-Founder, Michael Farr said “It’s a cool time for content creators and on-air personalities so in addition to in-house productions like “Director’s Spotlight hosted by James Ylisela,” other ABFAB.COM original programming, plus the amazing content that gets submitted to us, we will pay homage to the MTV era by casting VJ’s to intro films and host content on the channel. As submissions for the 6th Annual Transparent Film Festival are now closed, the festival's commitment to reviewing every film in its entirety sets it apart, providing valuable feedback to content creators and ensuring a fair evaluation process. ABFAB.COM seeks to offer viewers an alternative to mainstream platforms, focusing on independent content creation and delivering a quality viewing experience. Festival Judge, Marc Mifsud said “We take great pride in the fact that we review each and every film that is submitted and provide direct feedback to filmmakers, I think the people who submit feel good knowing that their film will be reviewed and not just end up in a pile of films that never get a chance to be truly judged.“ For tickets to this year's festival or more information about Transparent Film Festival and ABFAB.COM, visit www.transparentfilmfest.com Don't forget to tune in to Transparent TV on Manhattan Cable Channel 34 Spectrum every Friday night at 12 midnight ET. About Transparent Film Festival: Founded by Brian McLane, Transparent Film Festival celebrates independent filmmaking by honoring each submission with a thorough review process that includes full viewing of every film submitted. With over 2500 films submitted in its first five years, the festival remains dedicated to its mission and is now in its 6th year, aiming for IMDb certification. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com
May 16, 2024 02:40 PM Eastern Daylight Time
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Recce Pharmaceuticals doses highest cohort in phase I/II UTI/Urosepsis trial
RECCE PHARMACEUTICALS LTD
Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) managing director and CEO James Graham talks with Proactive’s Jonathan Jackson about how Recce has administered the first doses in the latest cohort of its Phase I/II clinical trial for urinary tract infection (UTI) and urosepsis treatment with RECCE® 327 (R327). Both male and female participants received R327 at 4,000mg intravenously (I.V.) over 20 minutes, marking the highest dosage in this trial to date. R327, an intravenous and topical therapy, is being developed to treat serious infections caused by Gram-positive and Gram-negative bacteria, including their superbug forms. The clinical trial has explored various infusion times for R327, including 15, 20, 30 and 45 minutes, across different dosage levels. This latest cohort involves the highest dose of 4,000mg, with Minimum Inhibitory Concentration (MIC) activity against bacteria identified in existing clinical samples. This dose optimisation is significant for regulatory purposes. Remaining participants will be dosed in the coming days, and the full potential of R327 via I.V. administration will be evaluated upon completion of the trial. Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 jonathan@proactiveinvestors.com
May 16, 2024 02:40 PM Eastern Daylight Time
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Anteris Technologies achieves breakthrough in triple valve replacement using DurAVR™
Anteris Technologies Ltd
Anteris Technologies Ltd (ASX:AVR, OTC:AMEUF) CEO Wayne Paterson sits down with Proactive’s Jonathan Jackson to discuss a complex 'valve-in-valve-in-valve' procedure completed using its DurAVR™ transcatheter aortic valve replacement (TAVR) system. This innovative biomimetic valve is made from a single piece of native-shaped tissue. The procedure was performed at Karolinska University Hospital in Stockholm, Sweden, by Dr Andreas Rück, Dr Magnus Settergren and Dr Nawzad Saleh. The patient, receiving a third valve replacement, had previously undergone a surgical valve replacement and a subsequent TAVR valve insertion, both of which failed. Due to the patient's high risk for surgical intervention and the inadequacy of existing TAVR devices, the heart team opted for the DurAVR™ system under compassionate use approval. The procedure was successful. Paterson highlights the ease of use and effectiveness of DurAVR™, noting its superior performance even in complex cases. He emphasises the unique capability of DurAVR™ to function in challenging environments, improving the patient’s condition significantly and points out the broader implications of biomimetic technology in achieving normal pre-disease hemodynamics in clinical trials. Paterson underscores DurAVR™'s unique profile and its potential as a valuable alternative in challenging cases. Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 Jonathan@proactiveinvestors.com
May 16, 2024 02:30 PM Eastern Daylight Time
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Torque Metals secures strategic tenement package in WA
TORQUE METALS LIMITED
Torque Metals Ltd (ASX:TOR) managing director Cristian Moreno sits down with Jonathan Jackson in the Proactive studio to discuss the completion of extension drilling at its wholly owned flagship Paris Gold Project, southeast of Kalgoorlie on the gold-rich Boulder-Lefroy Fault Zone. Assay results are imminent and a new drilling phase is being planned. Moreno also talks about an option agreement to acquire a 100% interest in a strategic package of tenements with gold and lithium potential in the Eastern Goldfields of Western Australia. This acquisition aligns with the company's strategy to consolidate prospective ground near its Penzance Exploration Camp, which includes the New Dawn lithium and Paris gold discoveries. The tenements span approximately 250 square kilometres, increasing Torque’s project area to around 1,200 square kilometres. This expansion will provide Torque with a dominant position in the region. The tenements are near notable projects such as Lord Resources' Horse Rocks, Future Battery Minerals’ Kangaroo Hills and Mineral Resources’ Mt Marion Lithium Project. These areas share similar geological characteristics, primarily greenstone belts with adjacent intrusions, indicating strong potential for gold and lithium. Torque has also applied for additional tenements to expand its New Dawn Lithium Project. Moreno highlighted that upon exercising the options, Torque would secure 100% ownership of the tenements, enhancing its portfolio to include 13 mining, four prospecting and 38 exploration licences. The company has initiated geological mapping and sampling at new target areas, preparing for initial drilling campaigns. Contact Details Proactive Investors Jonathan Jackson +61 413 713 744 jonathan@proactiveinvestors.com
May 16, 2024 02:15 PM Eastern Daylight Time
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Rubble set to Launch Groundbreaking Marketplace App to Reduce Construction Waste
Prodigy Press Wire
Rubble is set to launch a revolutionary marketplace app. It serves as a platform where leftover tools and materials can find new life, helping to reduce landfill waste and promote environmental sustainability. Rubble caters to contractors, homeowners, and do-it-yourself (DIY) enthusiasts, allowing them to list and purchase leftover construction materials. The innovative app's mission is to transform one person's trash into another's treasure by cleaning up spaces and keeping useful supplies out of landfills. Users can list their leftover materials in seconds and choose from categories such as appliances, electrical, bath and faucets, hardware, lumber, paint, and more. This ease of use encourages more people to participate, increasing the availability of materials. "We developed the app to emulate the experience of going through aisles in large-scale construction stores. Just like in those stores, users can browse through different sectors so they can effortlessly locate what they need within the app," Keara Sexton, the co-founder, shares. Rubble also includes an in-app messaging feature to facilitate easy communication between buyers and sellers. With this, all negotiations and arrangements can be handled smoothly within the platform. In addition, users can save their favorite posts in Rubble, allowing it to provide tailored recommendations based on their interests and past interactions. This personalized approach enhances user experience and helps buyers find exactly what they need for their projects. The launch of Rubble promises numerous benefits. Firstly, it's worth noting that the construction industry significantly contributes to landfill waste. Materials still in optimal condition often end up discarded after projects. Rubble addresses this issue by creating a marketplace that encourages the reuse of materials. Reducing the need for new materials helps offset the environmental impact associated with the extraction and production of these resources. Moreover, it presents more business opportunities within local communities, making construction projects more cost-effective and sustainable. "The fees for disposing of materials are expensive. We encourage commercial job sites to recycle and resell materials through Rubble, so they can save money on dump fees and make extra cash by selling unused materials that would otherwise just be discarded," Sexton remarks. This win-win scenario aligns with Rubble's mission of promoting sustainability while providing a financial incentive for users. The co-founder also envisions Rubble as a community-driven platform where users feel inclined to list items for free, contributing to a culture of sharing resources, all while reducing waste and championing sustainability. This philosophy especially resonates with homeowners and DIY enthusiasts, who may prioritize organizing their storage areas and giving their unused materials a chance to be utilized elsewhere. Rubble spearheads a movement toward a more sustainable construction industry. This app is bound to become the go-to marketplace for buying and selling leftover materials. After all, it offers a unique opportunity for individuals to contribute to a greener future while also saving money and decluttering their spaces. Media Contact Name: Keara Sexton Email: info@rubbleapp.com Release ID: 1025806
May 16, 2024 02:00 PM Eastern Daylight Time
